MICKLE, TRAVIS,GUENTHER, SVEN,MICKLE, CHRISTAL,CHI, GUOCHEN,KANSKI, JAROSLAW,MARTIN, ANDREA K.,BERA, BINDU
申请号：
AU2010266209
公开号：
AU2010266209A1
申请日:
2010.07.01
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The presently described technology provides phenylethanoic acid, phenylpropanoic acid, phenylpropenoic acid, a salt thereof, a derivative thereof or a combination thereof chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs or compositions of hydrocodone which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.
