Phenylethanoic acid, phenylpropanoic acid and phenylpropenoic acid conjugates and prodrugs of hydrocodone, method of making and use thereof

• 收藏
• 分享

专利权人:

KemPharm; Inc.

发明人:

Travis Mickle,Sven Guenther,Christal Mickle

申请号：

US14493611

公开号：

US09125947B2

申请日:

2014.09.23

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The presently described technology provides phenylethanoic acid, phenylpropanoic acid, phenylpropenoic acid, a salt thereof, a derivative thereof or a combination thereof chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs or compositions of hydrocodone which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/