LOCKWOOD, Charles, Joseph,KAYISLI, Umit, Ali,BASAR, Murat,GUZELOGLU-KAYISLI, Ozlem,SEMERCI, Nihan,SCHATZ, Frederick
申请号:
EP16769624
公开号:
EP3273980A4
申请日:
2016.03.23
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention concerns compositions and methods for inhibition of abnormal uterine bleeding (AUB), such as that associated with use of long-acting progestin-only contraceptives (LAPCs). An aspect of the invention concerns compositions comprising chemokine (C-C motif) ligand 2 (CCL2), or a biologically active fragment thereof, which may administered to subjects for inhibition of AUB. Another aspect of the invention concerns methods for inhibiting AUB, comprising administering an effective amount of CCL2, or a biologically active fragment thereof, to a subject in need thereof. Another aspect of the invention concerns a kit for inhibiting AUB.