CHARLES JOSEPH LOCKWOOD,UMIT ALI KAYISLI,MURAT BASAR,OZLEM GUZELOGLU-KAYISLI,NIHAN SEMERCI,FREDERICK SCHATZ
申请号：
US15561158
公开号：
US20180078615A1
申请日:
2016.03.23
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention concerns compositions and methods for inhibition of abnormal uterine bleeding (AUB), such as that associated with use of long-acting progestin-only contraceptives (LAPCs). An aspect of the invention concerns compositions comprising chemokine (C-C motif) ligand 2 (CCL2), or a biologically active fragment thereof, which may administered to subjects for inhibition of AUB. Another aspect of the invention concerns methods for inhibiting AUB, comprising administering an effective amount of CCL2, or a biologically active fragment thereof, to a subject in need thereof. Another aspect of the invention concerns a kit for inhibiting AUB.
