Fusokines involving cytokines with strongly reduced receptor binding affinities

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专利权人:

VIB VZW;Centre Hospitalier Regional Universitaire de Montpellier;Universiteit Gent;Centre National de la Recherche Scientifique;Universite Montpellier 2

发明人:

Tavernier, Jan,Bultinck, Jennyfer,Gerlo, Sarah,Uze, Gilles,Paul, Franciane,Bordat, Yann

申请号：

AU2014292371

公开号：

AU2014292371A1

申请日:

2014.07.03

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The present invention relates to a fusion protein comprising at least two cytokines, of which at least one is a modified cytokine with a strongly reduced binding affinity to its receptor, or to one of its receptors. Preferably, both cytokines are connected by a linker, preferably a GGS linker. The invention relates further to said fusion protein for use in treatment of diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/