Fusocins involving cytokines with strongly reduced receptor binding affinities

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专利权人:

Centre Hospitalier Régional Universitaire de Montpellier;VIB VZW;Université de Montpellier;Universiteit Gent;Centre National de la Recherche Scientifique

发明人:

TAVERNIER, Jan,BULTINCK, Jennyfer,GERLO, Sarah,UZE, Gilles,PAUL, Franciane,BORDAT, Yann

申请号：

ES17195867

公开号：

ES2757501T3

申请日:

2014.07.03

申请国别(地区):

ES

年份:

2020

代理人:

摘要：

The present invention relates to a fusion protein comprising at least two cytokines, of which at least one is a modified cytokine with a strongly reduced binding affinity to its receptor, or to one of its receptors. Preferably, both cytokines are connected by a linker, preferably a GGS linker. The invention relates further to said fusion protein for use in treatment of diseases.

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中国工程科技知识中心

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http://www.ckcest.cn/home/