FUSOKINES INVOLVING CYTOKINES WITH STRONGLY REDUCED RECEPTOR BINDING AFFINITIES

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专利权人:

VIB VZW;CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE MONTPELLIER;UNIVERSITEIT GENT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITÉ MONTPELLIER 2

发明人:

TAVERNIER, JAN,BULTINCK, JENNYFER,GERLO, SARAH,UZÉ, GILLES,PAUL, FRANCIANE,BORDAT, YANN

申请号：

SG11201600163V

公开号：

SG11201600163VA

申请日:

2014.07.03

申请国别(地区):

SG

年份:

2016

代理人:

摘要：

The present invention relates to a fusion protein comprising at least two cytokines, of which at least one is a modified cytokine with a strongly reduced binding affinity to its receptor, or to one of its receptors. Preferably, both cytokines are connected by a linker, preferably a GGS linker. The invention relates further to said fusion protein for use in treatment of diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/