SARDI, SERGIO PABLO,SHIHABUDDIN, LAMYA,CHENG, SENG
申请号:
PH12015500879
公开号:
PH12015500879A1
申请日:
2015.04.20
申请国别(地区):
PH
年份:
2015
代理人:
摘要:
This disclosure relates to methods for improving neural function in a mammal with a proteinopathy comprising administering a therapeutically effective amount of an agent that increases glucocerebrosidase activity in the mammal. Also disclosed are methods for reducing toxic lipids, reducing a-synuclein, and/or inhibiting the accumulation of protein aggregates in a mammal with a proteinopathy comprising administering a therapeutically effective amount of an agent that increases glucocerebrosidase activity.