SARDI, SERGIO PABLO,SHIHABUDDIN, LAMYA,CHENG, SENG
申请号:
SG11201502989X
公开号:
SG11201502989XA
申请日:
2013.11.04
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
This disclosure relates to methods for improving neural function in a mammal with a proteinopathy comprising administering a therapeutically effective amount of an agent that increases glucocerebrosidase activity in the mammal. Also disclosed are methods for reducing toxic lipids, reducing alpha-synuclein, and/or inhibiting the accumulation of protein aggregates in a mammal with a proteinopathy comprising administering a therapeutically effective amount of an agent that increases glucocerebrosidase activity.