SARDI, Sergio Pablo,SHIHABUDDIN, Lamya,CHENG, Seng
申请号:
MA38144
公开号:
MA38144A1
申请日:
2013.11.04
申请国别(地区):
MA
年份:
2018
代理人:
摘要:
This disclosure relates to methods for improving neural function in a mammal with a proteinopathy comprising administering a therapeutically effective amount of an agent that increases glucocerebrosidase activity in the mammal. Also disclosed are methods for reducing toxic lipids, reducing alpha-synuclein, and/or inhibiting the accumulation of protein aggregates in a mammal with a proteinopathy comprising administering a therapeutically effective amount of an agent that increases glucocerebrosidase activity.