TANG, YIQING; MATTHEW R.;LEWIS, ANDREW LENNARD;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE NATIONAL INSTITUTES OF HEALTH, A COMPONENT OF THE UNITED ;DREHER;DREHER, MATTHEW R.;WOOD, BRADFORD J.;NEGUSSIE, AYELE H.
发明人:
DREHER, MATTHEW R.,WOOD, BRADFORD J.,NEGUSSIE, AYELE H.,LEWIS, ANDREW LENNARD,TANG, YIQING
申请号：
CA2906574
公开号：
CA2906574A1
申请日:
2014.03.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
This invention concerns imageable, radiopaque embolic beads, which are particularly useful for monitoring embolization procedures. The beads comprise iodine containing compounds which are covalently incorporated into the polymer network of a preformed hydrogel bead. The beads are prepared by activating pre-formed hvdrogel beads towards nucleophilic attack and then covalently attaching iodinated compounds into the polymer network. The radiopaque beads may be loaded with chemotherapeutic agents and used in methods of embolizing hyperplastic tissue or solid tumors.
