Matthew R. DREHER,Bradford J. WOOD,Ayele H. NEGUSSIE,Andrew Lennard LEWIS,Yiqing TANG
申请号：
US16381204
公开号：
US20190328908A1
申请日:
2019.04.11
申请国别(地区):
US
年份:
2019
代理人:
摘要：
This invention concerns imageable, radiopaque embolic beads, which are particularly useful for monitoring embolization procedures. The beads comprise iodine containing compounds which are covalently incorporated into the polymer network of a preformed hydrogel bead. The beads are prepared by activating pre-formed hydrogel beads towards nucleophilic attack and then covalently attaching iodinated compounds into the polymer network. The radiopaque beads may be loaded with chemotherapeutic agents and used in methods of embolizing hyperplastic tissue or solid tumors.
