Dreher, Matthew R.,Wood, Bradford J.,Negussie, Ayele H.,Lewis, Andrew Leonard,Tang, Yiqing
申请号:
HK16108169.0
公开号:
HK1220119A
申请日:
2016.07.12
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
This invention concerns imageable, radiopaque embolic beads, which are particularly useful for monitoring embolization procedures. The beads comprise iodine containing compounds which are covalently incorporated into the polymer network of a preformed hydrogel bead. The beads are prepared by activating pre-formed hydrogel beads towards nucleophilic attack and then covalently attaching iodinated compounds into the polymer network. The radiopaque beads may be loaded with chemotherapeutic agents and used in methods of embolizing hyperplastic tissue or solid tumors.