PURPOSE: A pharmaceutical composition and a health functional food containing widdrol are provided to suppress proliferation and differentiation of pre-adipocytes and to effectively prevent and treat obesity.CONSTITUTION: A composition for suppressing proliferation and differentiation pre-adipocytes contains widdrol as an active ingredient. A composition for preventing and treating obesity contains widdrol as an active ingredient. The daily dose of widdrol in the composition is 100 ug/kg(body weight). The composition is manufactured in the form of an oral or parenteral formulation. A health functional food for preventing obesity contains widdrol. The health functional food is manufactured in the form of a powder, granules, a tablet, a capsule, a suspension, an emulsion, a syrup, a candy, snack, gum, ice cream, bread, and beverage.COPYRIGHT KIPO 2013본 발명은 위드롤(Widdrol)을 유효 성분으로 포함하는 지방전구세포 증식 및 분화 억제용 조성물, 및 비만 예방 및 치료용 약학 조성물을 제공한다. 또한, 본 발명은 위드롤을 유효 성분으로 포함하는 비만 예방용 건강기능식품을 제공한다.