您的位置: 首页 > 农业专利 > 详情页

METHODS FOR TREATING PSORIASIS
专利权人:
ЭББОТТ ЛЭБОРЕТРИЗ;ЭББОТТ ЛЭБОРЕТРИЗ;ЭББОТТ ГМБХ УНД КО. КГ
发明人:
ВАЛЬДЕС Хоакин Марио,ЧАРТАШ Эллиот К.,БАРЧУК Уилльям Т.,ПОЛСОН Сьюзан К.,ГОРДОН Кеннет В.,АВНИ Валид М.,БАО Яньжунь,ГЛАСС Уилльям Дж.,ГУ Ихуа,ХАРРИС Том К.,КАУЛ Мартин,МУЛАНИ Парвез М.,НЕРТЕРСХОЙЗЕР П
申请号:
RU2012114854
公开号:
RU2012114854A
申请日:
2010.09.14
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A method of treating psoriasis in an individual, comprising administering to said individual a first dose of an antibody or antigen binding portion thereof that are capable of binding to the p40 subunit of IL-12 and / or IL-23, with a first periodicity, and administering a second dose of said antibody or its antigen binding parts with the same frequency or with the second frequency for the treatment of psoriasis in an individual. 2. The method of claim 1, wherein the first dose of the antibody or antigen binding portion thereof is at least about 100 mg to 200 mg; at least about 100 mg; or at least about 200 mg. 3. The method of claim 1, wherein the second dose of the antibody or antigen binding portion thereof is at least about 200 mg; or at least about 100 mg. 4. The method of claim 1, wherein the second dose of the antibody or antigen binding part thereof is similar to the first dose of the antibody or antigen binding part thereof or differs from the first dose of the antibody or antigen binding part. The method according to claim 4, wherein the second dose of the antibody or antigen binding part thereof is about 40-60% of the first dose of the antibody or antigen binding part; or about 190-210% of the first dose of the antibody or antigen binding portion thereof. 6. The method according to claim 1, where the first frequency of administration of the antibody or its antigennegative part is approximately once a week; about once every other week; or about once every four weeks. 7. The method according to claim 1, where the duration of the cycle of administration with the first periodicity is approximately 8 weeks. The method according to claim 1, where the duration of the cycle of administration with a second frequency is at least about 12 weeks1. Способ лечения псориаза у индивидуума, включающий введение указанному индивидууму первой дозы антитела или его антигенсвязывающей части, которые обладают способностью связываться с субъединицей р40 IL-12 и/или IL-23, с п
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充