BARTRA SANMARTI MARTI,BERENGUER MAIMO RAMON,SOLSONA ROCABERT JOAN GABRIEL
申请号：
ZA201205320
公开号：
ZA201205320B
申请日:
2012.07.17
申请国别(地区):
ZA
年份:
2013
代理人:
摘要：
A preparation process of esomeprazole sodium substantially free of sulfone impurity including the steps of: a) combining either esomeprazole with a (C3-C8)-ketone or a mixture thereof, a sodium alkoxide, and a (C1-C5)-alcohol, or esomeprazole sodium with a (C3-C8)-ketone or a mixture thereof and a (C1-C5)-alcohol； and b) recovering the esomeprazole sodium formed from the reaction media by filtration.
