BARTRA SANMART MART,BERENGUER MAIM RAM³N,SOLSONA ROCABERT JOAN GABRIEL
申请号：
IN6454/CHENP/2012
公开号：
IN2012CN06454A
申请日:
2012.07.23
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
Preparation process of the sodium salt of a 2 (2 pyridylmethylsulfinyl) benzimidazole derivative compound It comprises a preparation process of esomeprazole sodium substantially free of sulfone impurity comprising the steps of: a) combining either esomeprazole with a (C C) ketone or a mixture thereof a sodium alkoxide and a (C C) alcohol or esomeprazole sodium with a (C C) ketone or a mixture thereof and a (C C) alcohol and b) recovering the esomeprazole sodium formed from the reaction media by filtration.
