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Sigma receptor ligation in colic pain
专利权人:
LABORATORIOS DEL DR. ESTEVE; S.A.
发明人:
PLATA-SALAMAN, CARLOS,RAMN - CEBRECOS-PREZ, JESS
申请号:
ARP170101927
公开号:
AR109024A1
申请日:
2017.07.11
申请国别(地区):
AR
年份:
2018
代理人:
摘要:
Claim 1: a salt, isomer, or solution pharmaceutically acceptable for the prevention and / or treatment of colic pain, in accordance with general formula (1) or salt, isomer, Prof á R, or solvato, wherein R1 is selected from a group of hydrogen, alternative, or unsubstituted bitumens, Alternative or unsubstituted, alternative or unsubstituted, alternative or unsubstituted, alternative or unsubstituted, alternative or unsubstituted, alternative or unsubstituted-C(O)Or831222,-C (o) No. 831222; (r8313);-CH=Nr.831222;-CN,Or831222,-OC(O)R831222,-S(o)8348;-R831222;-8312; 8313;-831222; (C (o) r8313;-No.8322;-N = cr831223; r8313 and halogen; R2 are selected from the components replaced or not replaced, substituted or not replaced, substituted or not replaced, substituted or not replaced, substituted or not replaced, substituted or not replaced, aromatic or non aromatic isocyclopentyl substituted or not replaced by hydrogen, substituted or not replaced tar, cyclopentyl, Substituted or unsubstituted isopropyl-C(O)Or831222,-C (o) No. 831222; (r8313);-CH=Nr.831222;-CN,Or831222,-OC(O)R831222,-S(o)8348;-R831222;-8312; 8313;-831222; (C (o) r8313;-No.8322;-N = cr83212; r8313 and halogen; R3 and r83088 are independently selected from hydrogen, substituted or unsubstituted asphalt, substituted or unsubstituted cyclopentadiene, substituted or unsubstituted halodiene, substituted or unsubstituted arilalquilo, aromatic or non aromatic isocyclohexane groups, respectively; Substituted or unsubstituted, substituted or unsubstituted heterosexual,-C(O)Or831222,-C (o) No. 831222; (r8313);-CH=Nr.831222;-CN,Or831222,-OC(O)R831222,-S(o)8348;-R831222;-8312; 8313;-831222; (C (o) r8313;-No.8322;-N=CR831223;R8313;a. Halogens, or together with halogens, form an alternative circumfluence condensation system; r83099 and r8310a are independently selected from a group consisting of hydrogen, substituted or unsubstituted tar, cyclopentyl substituted or unsubstituted halons, substituted or unsubstituted ari
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