JOHANNES AEBI,KURT AMREIN,WENMING CHEN,BENOIT HORNSPERGER,BERND KUHN,YONGFU LIU,HANS P. MAERKI,ALEXANDER V. MAYWEG,PETER MOHR,XUEFEI TAN,ZHANGUO WANG,MINGWEI ZHOU
申请号：
ARP120104439
公开号：
AR088989A1
申请日:
2012.11.27
申请国别(地区):
AR
年份:
2014
代理人:
摘要：
These compounds help treat chronic kidney disease, hypertension, thyroid conjunctivitis and Cushing syndrome. Claim 1: the compound of equation (1), wherein: R1,R2,R3 and r83088 were selected from h, hydrocarbyl, cyclomequine, cyclomethyl carat, cyclomequine, halotars, halogenated cyclomequine, oxyhydrogen, propoxy, halogenated alcohy, halogenated cyclomequine, cyclomequine, isocyclopropylene substitute, isocyclopropyl agave substitute, arilalquilo substitute and alien love substitute respectively. These substituted isopropylpyranoids, substituted isopropylpyranoids, substituted arilalqui and substituted isopropylpyranoids were replaced by r.1,R1 3 and r1.830808；O R2 and r830808 add together to form a double link, but if RZ and r83088 add together to form a double link, r8309es h； or R1 and R2 combine with carbon atoms to form a bicycle substitute or a heterosexual substitute, which is these bicycle substitutes and non bicycle substitutes； R2,R y RO R3 and r83088, together with the carbon atoms connected with them, form a kind of rotary electrolysis or a kind of alternative of heterocyclic electrolysis, which are replaced by r8313；R³⁰ and R³¹；O R1 and R3, together with the carbon atoms connected with them, form a kind of rotary electrolysis or a kind of alternative of heterocyclic electrolysis, which are replaced by r8308； 830808；R8308；]A1 is Cr 831222 or N； A2 is cr8313 or N； A3 is cr183044 or N； a83081 or N； a83090 is Cr 8310 or N； 1 is r830909；R8310,R831181 and r831222 should be selected between halogen, cyanogen, oxygen, oxy, halogen, oxy and oxyhydrogen, and other substances should be selected independently between H, halogen, cyanogen, oxygen, oxyhydrogen, halogen and hydroxy； r8313 is h, halogen, hxi, cyanogen, alkyl, hydroxy, halogen, halide, epoxy, cyclohexane, cyclohexane, cyclohexane； Asphalt, halogenated cyclopropyl, liquefied gas clalquilo, acoxyclolaquilo, alcoxicyclelaquilo, halocyclolaquilaquilo, cyclolaquilacoxi, cycloaquidro, cyclocyclocyclocycloac
