COMPOSTOS ANTIMALÁRICOS COM CADEIAS LATERAIS FLEXÍVEIS

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专利权人:

MMV MEDICINES FOR MALARIA VENTURE

发明人:

YONGYUTH YUTHAVONG,TIRAYUT VILAVAIN,SUMALEE KAMCHONWONGPAISAN,BONGKOCH TARCHOMPOO,CHAWANEE THONGPANCHANG,PENCHIT CHITNUMSUB,JIRUNDON YUVANIYAMA,DAVID MATTHEWS,SUSAN CHARMAN,WILLIAM CHARMAN,LIVIA VIVAS

申请号：

PT08837766

公开号：

PT2194985T

申请日:

2008.10.08

申请国别(地区):

PT

年份:

2019

代理人:

摘要：

The present invention relates to novel compounds that are inhibitors of wild type and mutant dihydrofolate reductase (DHFR) ofwhich are useful for the treatment of malaria. It also relates to processes of making and using such compounds. The antimalarial compounds of the present invention have low toxicity to a host infected with the malarial parasite, and are potent when administered in pharmaceutical compositions.

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中国工程科技知识中心

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http://www.ckcest.cn/home/