ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS

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专利权人:

发明人:

YUVANIYAMA JIRUNDON,CHARMAN SUSAN,CHARMAN WILLIAM,KATIYAR SANJAY BABU,TARNCHOMPOO BONGKOCH,YUTHAVONG YONGYUTH,VILAIVAN TIRAYUT,CHITNUMSUB PENCHIT,THONGPANCHANG CHAWANEE,KAMCHONWONGPAISAN SUMALEE,VIVAS

申请号：

IN1507/KOLNP/2010

公开号：

IN281417B

申请日:

2010.04.29

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

The present invention relates to novel compounds that are inhibitors of wild type and mutant dihydrofolate reductase (DHFR) of Plasmodium falciparum, which are useful for the treatment of malaria. It also relates to processes of making and using such compounds. The antimalarial compounds of the present invention have low toxicity to a host infected with the malarial parasite, and are potent when administered in pharmaceutical compositions.

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中国工程科技知识中心

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http://www.ckcest.cn/home/