Antimalarial compounds with flexible side-chains

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专利权人:

MMV Medicines for Malaria Venture

发明人:

Yuthavong, Yongyuth,Vilaivan, Tirayut,Kamchonwongpaisan, Sumalee,Tarnchompoo, Bongkoch,Thongpanchang, Chawanee,Chitnumsub, Penchit,Yuvaniyama, Jirundon,Matthews, David,Charman, Susan,Charman, William

申请号：

AU2008310898

公开号：

AU2008310898B2

申请日:

2008.10.08

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The present invention relates to novel compounds that are inhibitors of wildtype and mutant dihydrofolate reductase (DHFR) of Plasmodium falciparum, whichare useful for the treatment of malaria. It also relates to processes of makingand using such compounds. The antimalarial compounds of the present inventionhave low toxicity to a host infected with the malarial parasite, and are potentwhen administered in pharmaceutical compositions.

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中国工程科技知识中心

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