DOLABELA, MARIA FÂNI,MARTINS, MICHEL T.,BRANDÃO, DAYSE LÚCIA DONASCIMENTO,BORGES, EDINILZA DA SILVA,PERCÁRIO, SANDRO,MARINHO, ANDREY MOACIR DO R.,SILVA, THIAGO L. DA,VILHENA, THYAGO DA COSTA,VASCONCEL
申请号：
EP13787415
公开号：
EP2851081A4
申请日:
2013.05.13
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
The present invention describes the obtaining process of the dichloromethane fraction and subfractions from Eleutherine plicata, popularly known as "marupazinho, maruparí, palmeirinha, coquinho, marupaí, marupaú, marupá-piranga, and lírio-folha-de-palmeira". This invention comprises the obtaining process of pharmaceutical compositions that contain the dichloromethane fraction and/or naphthoquinone, as well as its use for malaria treatment. Extract and fractions were assayed and presented antiplasmodial activity, particularly against chloroquine-resistant Plasmodium falciparum (clone W2).
