UNIVERSIDADE FEDERAL DO PARA-UFPA;UNIVERSEDADE FEDERAL DE MINAS GERAIS-UFMG;MUSEU PARAENSE EMILIO GOELDI;INSTITUTO EVANDRO CHAGAS;SECRETARIA EXECUTIVA DE SAUDE PUBLICA DO ESTADO DO PARA
发明人:
Maria Fani Dolabela,Michel T. Martins,Dayse Lucia do Nascimento Brandao,Edinilza da Silva Borges,Sandro Percario,Andrey Moacir do R. Marinho,Thiago L. da Silva,Thyago da Costa Vilhena,Flavio de Vascon
申请号：
US14400479
公开号：
US20150132421A1
申请日:
2013.05.13
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention describes the obtaining process of the dichloromethane fraction and subfractions from Eleutherine plicata, popularly known as “marupazinho, marupari, palmeirinha, coquinho, marupaí, marupaú, marupá-piranga, and lirio-folha-de-palmeira”. This invention comprises the obtaining process of pharmaceutical compositions that contain the dichloromethane fraction and/or naphthoquinone, as well as its use for malaria treatment. Extract and fractions were assayed and presented antiplasmodial activity, particularly against chloroquine-resistant Plasmodium falciparum (clone W2).
