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C2-FLUORO SUBSTITUTED PIPERAZINE LINKED PYRROLO[2,1-C)[1,4]BENZODIAZEPINE DIMERS AND A PROCESS FOR THE PREPARATION THEREOF
专利权人:
发明人:
AHMED KAMAL,RAJENDER,METUKU KASHIREDDY,GORRE BALAKISHAN
申请号:
IN608/DEL/2008
公开号:
IN278139B
申请日:
2008.03.11
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention provides a compounds of general formula IXa-d, useful as potential antitumour agents and pharmaceutical composition comprising these compounds exhibits binding affinity with calf thymus (CT) DNA at a molar ratio of 1:5 in aqueous sodium phosphate buffer at pH of 7.00. The present invention further provides a process for the preparation of C2-Fluoro substituted piperazine linked pyrrolo[2,1 c][1,4]benzodiazepine of formula IX.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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