Pierre Lafaye,Jean-Pierre Bourgeois,Francois Rougeon
申请号:
US13002910
公开号:
US08460888B2
申请日:
2009.07.07
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to the use of variable domains of camelid heavy-chain antibodies (VHH domains) directed against an intracellular target and having an isoelectric point of at least 8.5, for targeting said intracellular target or for the preparation of a peptide vector. Particularly, it concerns VHH domains directed against a glial fibrillary acidic protein and uses thereof for preparing therapeutic or diagnostic agents.