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VARIABLE DOMAINS OF CAMELID HEAVY-CHAIN ANTIBODIES DIRECTED AGAINST GLIAL FIBRILLARY ACIDIC PROTEINS
专利权人:
发明人:
Pierre LAFAYE,Jean-Pierre BOURGEOIS,Francois ROUGEON
申请号:
US15442794
公开号:
US20170165383A1
申请日:
2017.02.27
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to the use of variable domains of camelid heavy-chain antibodies (VHH domains) directed against an intracellular target and having an isoelectric point of at least 8.5, for targeting said intracellular target or for the preparation of a peptide vector. Particularly, it concerns VHH domains directed against a glial fibrillary acidic protein and uses thereof for preparing therapeutic or diagnostic agents.
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