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Variable domains of camelid heavy-chain antibodies directed against glial fibrillary acidic proteins
专利权人:
Centre National De La Recherche Scientifique;Institut Pasteur
发明人:
Rougeon, Francois,Bourgeois, Jean-Pierre,Lafaye, Pierre
申请号:
AU2009269698
公开号:
AU2009269698B2
申请日:
2009.07.10
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to the use of variable domains of camelid heavy-chain antibodies (VHH domains) directed against an intracellular target and having an isoelectric point of at least 8.5, for targeting said intracellular target or for the preparation of a peptide vector. Particularly, it concerns VHH domains directed against a glial fibrillary acidic protein and uses thereof for preparing therapeutic or diagnostic agents.
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