The present invention relates to novel topical pharmaceutical compositions comprising an oxazolidin-2-one-pyrimidine compound of formula (I),a method of manufacturing such compositions, as well as uses of such compositions. The present invention also relates to a novel crystalline form of the compound of formula (I).本發明係關於包含式(I)㗁唑啶-2-酮-嘧啶化合物之新穎性局部醫藥組合物,,製造此等組合物之方法,以及此等組合物之用途。本發明亦關於一種式(I)化合物之新穎性結晶形態。