Helmholtz Zentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt GmbH
发明人:
Schendel, Dolores,Wilde, Susanne,Blankenstein, Thomas
申请号：
HUE10179257
公开号：
HUE038833T2
申请日:
2006.08.04
申请国别(地区):
HU
年份:
2018
代理人:
摘要：
The present invention is directed to a method of generating antigen specific T cells. Furthermore, the invention is directed to antigen specific T cells, isolated transgenic TCRs, pharmaceutical compositions containing same and their use in adoptive cell therapy. This invention in particular pertains to the use of cells co-expressing allogeneic MHC molecules and antigens to induce peptide-specific T cells from non-selected allogeneic T cell repertoires.
