Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH;Max-Delbrück-Centrum für Molekulare Medizin (MDC)
发明人:
SCHENDEL, DOLORES,WILDE, SUSANNE,BLANKENSTEIN, THOMAS
申请号：
PL10179257
公开号：
PL2327763T3
申请日:
2006.08.04
申请国别(地区):
PL
年份:
2018
代理人:
摘要：
The present invention is directed to a method of generating antigen specific T cells. Furthermore, the invention is directed to antigen specific T cells, isolated transgenic TCR's, pharmaceutical compositions containing same and their use in adoptive cell therapy. This invention in particular pertains to the use of cells co-expressing allogeneic MHC molecules and antigens to induce peptide-specific T cells from non-selected allogeneic T cell repertoires.
