BISPECIFIC ANTIGEN MOLECULE FOR LYSIS OF TUMOR CELLS, METHOD FOR PREPARING F(AB')2 FRAGMENT OF BISPECIFIC ANTIGEN MOLECULE, MONOCLONAL ANTIBODY (VERSIONS), PHARMACEUTICAL PREPARATION, PHARMACEUTICAL KIT FOR LYSIS OF TUMOR CELLS (VERSIONS), METHOD OF LYSIS OF TUMOR CELLS EX VIVO IN AUTOGENOUS BONE MARROW TRANSPLANTATION

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专利权人:

发明人:

申请号：

RU19940028282

公开号：

RU2203319(C2)

申请日:

1994.08.01

申请国别(地区):

俄罗斯

年份:

2003

代理人:

摘要：

FIELD: biotechnology, medicine, oncology, pharmacy. SUBSTANCE: invention relates to bispecific molecule of antigen that recognizes antigen of lymphocytes CD2 and any variable tumor antigen. Except for, invention relates to two novel monoclonal antibodies designated as AICD2.M1 and AICD2.M2. Combination of these antibodies one of that at least represents bispecific antigen molecule can be used in pharmaceutical preparation or kit successively for therapy and diagnosis of tumors. EFFECT: improved preparing method, valuable medicinal properties of preparation and kit. 13 cl, 9 dwg, 12 ex

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