BioNTech RNA Pharmaceuticals GmbH;TRON-Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-Universitat Mainz gG
发明人:
Ugur Sahin,Heinrich Haas,Sebastian Kreiter,Mustafa Diken,Daniel Fritz,Martin Meng,Lena Mareen Kranz,Kerstin Reuter
申请号：
US16578601
公开号：
US20200085974A1
申请日:
2019.09.23
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention is in the field of immunotherapy, in particular tumor immunotherapy. The present invention provides pharmaceutical formulations for delivering RNA to antigen presenting cells such as dendrite cells (DCs) in the spleen after systemic administration. In particular, the formulations described herein enable to induce an immune response after systemic administration of antigen-coding RNA.
