BIONTECH RNA PHARMACEUTICALS GMBH;TRON-TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZ GEMEINNÜTZIGE GMBH
发明人:
Ugur Sahin,Heinrich Haas,Sebastian Kreiter,Mustafa Diken,Daniel Fritz,Martin Meng,Lena Mareen Kranz,Kerstin Reuter
申请号：
US14388192
公开号：
US10485884B2
申请日:
2013.03.25
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention is in the field of immunotherapy, in particular tumor immunotherapy. The present invention provides pharmaceutical formulations for delivering RNA to antigen presenting cells such as dendrite cells (DCs) in the spleen after systemic administration. In particular, the formulations described herein enable to induce an immune response after systemic administration of antigen-coding RNA.
