Universitatsmedizin der Johannes Gutenberg-Universitat Mainz;Tron - Translationale Onkologie an der Johannes Gutenberg-Universitat Mainz Gemeinnutzige GmbH;BioNTech AG
发明人:
Sahin, Ugur,Haas, Heinrich,Kreiter, Sebastian,Diken, Mustafa,Fritz, Daniel,Meng, Martin,Kranz, Lena Mareen,Reuter, Kerstin
申请号：
AU2013242512
公开号：
AU2013242512A8
申请日:
2013.03.25
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention is in the field of immunotherapy, in particular tumor immunotherapy. The present invention provides pharmaceutical formulations for delivering RNA to antigen presenting cells such as dendrite cells (DCs) in the spleen after systemic administration. In particular, the formulations described herein enable to induce an immune response after systemic administration of antigen-coding RNA.
