BIONTECH RNA PHARMACEUTICALS GMBH;TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITATZSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ GEMEINNUTZIGE GMBH
发明人:
DIKEN, MUSTAFA,FRITZ, DANIEL,HAAS, HEINRICH,KRANZ, LENA MAREEN,KREITER, SEBASTIAN,MENG, MARTIN,REUTER, KERSTIN,SAHIN, UGUR
申请号：
CA3088428
公开号：
CA3088428A1
申请日:
2013.03.25
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention is in the field of immunotherapy, in particular tumor immunotherapy. The present invention provides pharmaceutical formulations for delivering RNA to antigen presenting cells such as dendrite cells (DCs) in the spleen after systemic administration. In particular, the formulations described herein enable to induce an immune response after systemic administration of antigen-coding RNA.
