COMPOSES 1, 3-DIHYDRO-ISOINDOLYLE A SUBSTITUTION FLUOROALCOXY ET LEURS UTILISATIONS PHARMACEUTIQUES

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专利权人:

CELGENE CORPORATION

发明人:

MULLER, GEORGE W.,MAN, HON-WAH,ZHANG, WEIHONG

申请号：

CA2511843

公开号：

CA2511843C

申请日:

2003.12.29

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

The invention encompasses a novel compound of formula I:(see formula I)its pharmaceutically acceptable salts, hydrates, solvates, clathrates,enantiomers,diastereomers, racemates, or mixtures of stereoisomers, pharmaceuticalcompositions comprising a compound of formula I, wherein R1, R2, X1, X2, X3,X4,Y and Z are as defined herein, and methods of use of the compound of formula Iand compositions comprising thereof in mammals for treatment or prevention ofdiseases associated with unregulated levels of PDE4.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/