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TYROSINASE INHIBITOR OBTAINED USING DRY POWDER FROM RAINWORKS AND METHOD FOR PRODUCING IT
专利权人:
ВЕЛЛ СТОУН КО. (JP)
发明人:
ИСИИ Йоити (JP),ИСИИ Казуюки (JP)
申请号:
RU2014107467/15
公开号:
RU2014107467A
申请日:
2012.07.24
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A method of obtaining a tyrosinase inhibitor, comprising the steps of: making contact of live earthworms with chloride (s) of at least one metal selected from the group consisting of potassium, sodium, magnesium and calcium; followed by making contact of these live earthworms with a hydroxycarboxylic acid powder, diluting the resulting mixture with water to bring the pH to 2-5 and then keeping the resulting diluted mixture for 3-180 minutes, or making contact of these live earthworms with an aqueous solution of hydroxycarboxylic acid, having a pH of 2-5, and then maintaining the resulting mixture for 3-180 minutes; followed by washing the living earthworms with water, crushing the washed earthworms, and then lyophilizing the resulting crushed product. 2. The method for producing a tyrosinase inhibitor according to claim 1, comprising the step of keeping live earthworms in a lighted place for 10-50 hours, separating dirt adhering to the surface of their body, followed by contacting the living earthworms with the indicated metal chloride (s) (s) ), where this stage is performed until the contact of live earthworms with the specified chloride (s) is made. 3. A method for producing a tyrosinase inhibitor according to claim 1, wherein said lyophilization is carried out by freezing the crushed product at a temperature of from -18 ° C to -35 ° C for 20-240 hours, followed by lyophilization of the obtained product in vacuum. A method for producing a tyrosinase inhibitor according to claim 1, comprising the step of dissolving said lyophilized ground product in water, followed by removal or separation of the insoluble fraction. Cosmetic1. Способ получения ингибитора тирозиназы, включающий этапы:создания контакта живых дождевых червей с хлоридом(ами) по меньшей мере одного металла, выбранного из группы, состоящей из калия, натрия, магния и кальция; с последующим созданием контакта этих живых дождевых червей с порошком гидроксикарбоновой кислоты, разбавлением полученной смес
来源网站:
中国工程科技知识中心
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