NOUVEAUX COMPOSES D'IMIDAZOPYRIDINE SUBSTITUES EN TANT QU'INHIBITEURS D'INDOLEAMINE 2,3-DIOXYGENASE ET/OU DE TRYPTOPHANE-2,3-DIOXYGENASE

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专利权人:

MERCK SHARP & DOHME CORP.;IOMET PHARMA LTD.

发明人:

COWLEY, PHILLIP M.,MCGOWAN, MEREDETH ANN,BROWN, THOMAS J.,HAN, YONGXIN,LIU, KUN,PU, QINGLIN,WISE, ALAN,ZHANG, HONGJUN,ZHOU, HUA

申请号：

CA3021589

公开号：

CA3021589A1

申请日:

2017.04.24

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Disclosed herein are substituted imidazopyridine compounds of formula (I) which are inhibitors of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan-2,3-dioxygenase (TDO) enzymes: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder.

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