Phillip M. COWLEY;Meredeth Ann MCGOWAN;Thomas J. BROWN;WISE Alan;Hua ZHOU;Yongxin HAN;Kun LIU;Qinglin PU;Hongjun ZHANG;IOMet Pharma Ltd.
发明人:
Phillip M. Cowley,Meredeth Ann McGowan,Thomas J. Brown,Yongxin Han,Kun Liu,Qinglin Pu,Alan Wise,Hongjun Zhang,Hua Zhou
申请号:
US16088873
公开号:
US20200230117A1
申请日:
2017.04.24
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are substituted imidazopyridine compounds of formula (I) which are inhibitors of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan-2,3-dioxygenase (TDO) enzymes: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder.