NEUARTIGE SUBSTITUIERTE IMIDAZOPYRIDINVERBINDUNGEN ALS INHIBITOREN DER INDOLAMIN-2,3-DIOXYGENASE UND/ODER TRYPTOPHAN-2,3-DIOXYGENASE

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专利权人:

Iomet Pharma Ltd.;Merck Sharp & Dohme Corp.

发明人:

COWLEY, Phillip, M.,MCGOWAN, Meredeth Ann,BROWN, Thomas, J.,HAN, Yongxin,LIU, Kun,PU, Qinglin,WISE, Alan,ZHANG, Hongjun,ZHOU, Hua

申请号：

EP17790165

公开号：

EP3448522A4

申请日:

2017.04.24

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Disclosed herein are substituted imidazopyridine compounds of formula (I) which are inhibitors of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan-2,3-dioxygenase (TDO) enzymes: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder.

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