GERMAY, OLIVIER C.,GODART, STEPHANE ANDRE,HARVENGT, POL GUY,LAANAN, AMINA,LE BUSSY, OLIVIER PATRICK,LEMOINE, DOMINIQUE INGRID,DODE, LEONARD
申请号：
CA2841380
公开号：
CA2841380A1
申请日:
2012.07.20
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to methods for the purification of PRAME. In particular the present invention relates to a method for reducing the aggregation of PRAME during a diluent exchange from diluent A to diluent B comprising: (i) adding a polyanionic compound to diluent A prior to or contemporaneously with the exchange； and (ii) exchanging protein from diluent A to diluent B. Compositions produced by the method are also provided.
