Germay, Olivier C.,Godart, Stephane Andre,Harvengt, Pol Guy,Laanan, Amina,Le Bussy, Olivier Patrick,Lemoine, Dominique Ingrid,Dode, Leonard
申请号：
AU2012288926
公开号：
AU2012288926A1
申请日:
2012.07.20
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention relates to methods for the purification of PRAME. In particular the present invention relates to a method for reducing the aggregation of PRAME during a diluent exchange from diluent A to diluent B comprising: (i) adding a polyanionic compound to diluent A prior to or contemporaneously with the exchange； and (ii) exchanging protein from diluent A to diluent B. Compositions produced by the method are also provided.
