Die vorliegende Erfindung betrifft die Verwendung mindestens eines Dicyclohexylmethanolderivats der Formel I als antimikrobieller Wirkstoff oder als Anti-Akne-, Antischuppen-, Deodorant- oder Antitranspirantwirkstoff, Zubereitungen enthaltend diese Verbindungen, sowie spezielle Diyclohexylmethanolderivate und ein Verfahren zu deren Herstellung.Use of substituted dicyclohexylmethanol derivatives (I) as an antimicrobial active substance, is claimed. Use of substituted dicyclohexylmethanol derivatives of formula (I) as an antimicrobial active substance and an anti-acne-, antidandruff-, deodorant- or antiperspirant active substance, is claimed. R1-R10 : H, OH, OCOCH 3, CH 2OH, SO 3H, halo, 1-20C alkyl or 1-20C alkoxy. Provided that at least one of the groups R1-R10 is OH or alkoxy group having 1-20 carbon atoms. Independent claims are also included for: (1) a formulation comprising (I) and at least one carrier (2) preparing the formulation, comprising mixing (I) with the carrier (3) (I) and (4) preparing (I). [Image] ACTIVITY : Antimicrobial Antiseborrheic Dermatological. The antibacterial activity of (I) was tested against Staphylococcus epidermidis (strain ATCC 12228). The results showed that 4-(cyclohexyl-hydroxy-methyl)-cyclohexanol (2% in water-(12%) ethanol mixture) decreased colony forming units from 1.6x 10 4> to 7.4x 10 3>. MECHANISM OF ACTION : None given.
