EDMONDSON, SCOTT,GUO, ZHIQIANG,GEISS, WILLIAM B.,WOOD, HAROLD B.,STAMFORD, ANDREW W.,MILLER, MICHAEL W.,DEMONG, DUANE E.,MORRIELLO, GREGORI J.,ANAND, RAJAN,COLANDREA, VINCENT J.,MACALA, MEGAN,MALETIC,
申请号:
CA2831334
公开号:
CA2831334A1
申请日:
2012.04.05
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Substituted cyclopropyl compounds of the formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and methods of treatment are also included