Scott Edmondson,Zhiyong Hu,Ping Liu,Gregori J. Morriello,Jason W. Szewczyk,Bowei Wang,Liping Wang,Harold B. Wood,Cheng Zhu,Yuping Zhu,Zhiqiang Guo
申请号:
US14358241
公开号:
US09018224B2
申请日:
2012.11.09
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Substituted cyclopropyl compounds of the formula (I): and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and methods of treatment are also included.