Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment

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专利权人:

Merck Sharp & Dohme Corp.

发明人:

Edmondson, Scott,Guo, Zhiqiang,Geiss, William B.,Wood, Harold B.,Stamford, Andrew W.,Miller, Michael W.,Demong, Duane E.,Morriello, Gregori J.,Anand, Rajan,Colandrea, Vincent J.,Macala, Megan,Maletic,

申请号：

AU2012240122

公开号：

AU2012240122B2

申请日:

2012.04.05

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

Substituted cyclopropyl compounds of the formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and methods of treatment are also included

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