MILLER, MICHAEL,STAMFORD, ANDREW,BASU, KALLOL,WOOD, HAROLD B.,DEMONG, DUANE,SUN, WANYING,GARFUNKLE, JOIE,MOYES, CHRISTOPHER,HU, ZHIYONG,LIU, PING,EDMONDSON, SCOTT D.,DAI, XING,DUBOIS, BYRON GABRIEL
申请号:
CA2838079
公开号:
CA2838079A1
申请日:
2012.06.11
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Substituted cyclopropyl compounds of the formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR-119. Pharmaceutical compositions and methods of treatment are also included.