NOVEL 6-TRIAZOLOPYRIDAZINESULFANYL BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND APPLICATION AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS AND NOVEL USE AS MET INHIBITORS
ALBERT EVA,BACQUE, ERIC,NEMECEK CONCEPTION,UGOLINI ANTONIO,WENTZLER SYLVIE
申请号：
MYPI 2010000582
公开号：
MY152535A
申请日:
2008.08.06
申请国别(地区):
MY
年份:
2014
代理人:
摘要：
THE INVENTION RELATES TO NOVEL PRODUCTS OF FORMULA (I): WHERE ---- IS A SINGLE OR DOUBLE BOND, RA = H, HAL, ALKOXY, O-CYCLOALKYL, HETEROARYL, PHENYL, NHCOALK, NHCOCYCLOALK OR NR1 R2； X = S, SO OR SO2； A = NH OR S； W = H, ALKYL OR COR WITH R = CYCLOALKYL； ALKYL, OPTIONALLY SUBSTITUTED WITH NR3R4, ALKOXY, HYDROXY, PHENYL, HETEROARYL, OR HETEROCYCLOALKYL； ALKOXY OPTIONALLY SUBSTITUTED BY NR3R4, IN OTHER WORDS A O-(CH2)N-NR3R4 GROUP, A O-PHENYL OR O-(CH2)N-PHENYL GROUP, WITH THE PHENYL OPTIONALLY SUBSTITUTED AND N= 1 TO 4； WHERE IN THE NR1 R2 GROUP； R1 = H OR ALK AND R2 = H, CYCLOALKYL OR ALKYL； R3 AND R4 = H, ALK, CYCLOALKYL, HETEROARYL OR PHENYL, R1, R2 AND/OR R3.R4 FORM A RING WITH N OPTIONALLY INCLUDING O, S, N AND/OR NH； ALL HETEROCYCLOALKYL, HETEROARYL AND PHENYL AND CYCLIC GROUPS BEING OPTIONALLY SUBSTITUTED, SAID PRODUCTS BEING IN ALL THE ISOMERIC FORMS AND ALL SALTS AS MEDICAMENTS IN PARTICULAR AS MET INHIBITORS.
