DERIVATIVES OF 6-(6-NH-SUBSTITUTED-TRIAZOLOPYRIDAZINE-SULFANYL) BENZOTHIAZOLES AND BENZIMIDAZOLES, PREPRATION THEREOF, USE THEREOF AS DRUGS, AND USE THEREOF AS MET INHIBITORS
- 专利权人:
- 发明人:
- BACQUE ERIC,NEMECEK CONCEPTION,UGOLINI ANTONIO,WENTZLER SYLVIE
- 申请号：
- IN3177/KOLNP/2011
- 公开号：
- IN2011KN03177A
- 申请日:
- 2011.07.27
- 申请国别(地区):
- IN
- 年份:
- 2012
- 代理人:
- 摘要：
The invention relates to novel products of the formula (I) where: (II) is a single or double bond Rb is a hydrogen or fluorine atom Ra is a NH-Rc radical in which Rc is an optionally substituted heterocycloalkyl, aryl, heteroaryl or -alkylcycloalkyl radical X is S, SO, or SO2 A is NH or S W is H, alkyl, or COR with R being cycloalkyl alkyl alkoxy O-phenyl -O- (CH2)n-phenyl with n= 1 to 4 or NR1R2 with R1 being H or alk and R2 is H, cycloalkyl or alkyl or R1, R2 form a cycle together with N optionally containing O, S, N and/or NH all of said radicals being optionally substituted wherein said products can be in any isomer or salt form, and can be used as drugs, in particular as MET inhibitors.
[WO2010089508A1]
- 来源网站：
- 中国工程科技知识中心
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